Youssef Ezzyat PhD

University of Pennsylvania

Dr. Ezzyat is a research scientist at the University of Pennsylvania whose work focuses on understanding the electrophysiological mechanisms of memory formation in order to develop stimulation-based therapies for treating memory dysfunction. His current work as part of a multi-center DARPA-funded project applies methods from machine learning to develop models that relate neural activity to memory outcomes, which are used to guide closed-loop direct brain stimulation for memory restoration. Using this approach, Dr. Ezzyat has shown that stimulation improves memory performance, suggesting a strategy for therapeutically treating memory dysfunction. Prior to his work investigating stimulation for memory restoration, Dr. Ezzyat used fMRI to study the roles of the hippocampus and frontal lobes in the formation of memories for complex episodic events.