Suman Dutta PhD

University of California, Los Angeles

Suman Dutta received his Ph.D. from the University of Kalyani, India. During his early research career he worked on mechanisms of metal stress induced macrophage apoptosis. During his postdoctoral study in Hallym University, South Korea he worked on neurotherapeutics, constructed full-length Pep1-Uchl-1 proteins of human origin and evaluated their transduction efficiency and preventive roles in neurodegenerative conditions. Then, he moved to the field of exosome biology and in Mahidol University, Thailand he worked exclusively on the role of exosomes in cholangiocarcinoma, an incurable, invasive and highly metastatic adenocarcinoma. He was the first to work with exosomes in the entire country and have established and standardized the working protocol for exosome isolation and characterization from several different cholangiocarcinoma patient derived cells. Since then, his work has focused on exosomes, mostly from healthy persons’ and patients’ samples, as well as cell lines, with the goals of characterizing and identifying signature molecules to use as biomarkers for different cancers and neurodegenerative diseases. Currently, in the Bitan lab at UCLA he is interested in studying exosomes for their role in spreading of amyloidogenic proteins and as potential biomarkers for neurodegenerative diseases, primarily focused on Parkinson’s disease (PD) and multiple system atrophy (MSA).