Sophie Lan-Linh Duong MD

Yale School of Medicine

Sophie Lan-Linh Duong is a sixth-year medical student at Johann Wolfgang Goethe University, Frankfurt, Germany. As a research scholar, she has been working with Dr. Ehrlich at Yale School of Medicine, investigating the effects of specific mutations in the gene of polycystin 2 on calcium signaling in autosomal dominant polycystic kidney disease and their link to idiopathic dilated cardiomyopathy. Her research has shown that decreased level of polycystin 2 result in alterations of adrenergic signaling in the heart, leading to cardiac dysfunction, independent of renal impairment. Her current research and clinical interest has shifted towards the field of neurology. During her neurology elective at Yale School of Medicine, she has been working with Dr. Baehring on characterizing neurotoxicities associated with immune checkpoint inhibitor therapy. She also has a strong interest in medical education and has established the curriculum for a new class in the “Institute of Physiology” at Johann Wolfgang Goethe University, teaching pre-clinical medical students the fundamental principles of physiology and pathophysiology. She hopes to matriculate into a neurology residency program with a strong focus on research and medical education.