Multiple Sclerosis - Inflammation Across Neurodegenerative Diseases: Implications for MS

Date/Time: Monday, October 22, 2018 - 3:30 PM to 5:30 PM
Type: Special Interest Group
Area: Multiple Sclerosis
Room: Regency VII

Session Overview

Chair: Justin C. McArthur, MBBS, MPH, FAAN – Johns Hopkins University Co-Chair: Ellen Mowry, MD, MCR – Johns Hopkins University There is growing evidence that obesity and related comorbidities play a role in multiple sclerosis (MS) risk and prognosis. This SIG will focus on the epidemiologic evidence supporting the role of obesity (and on relevant underlying biological mechanisms) in MS. Data from randomized controlled trials in MS as well as a discussion regarding the challenges of their conduct and interpretation will be presented. Data blitz speakers will be selected from submitted abstracts that address related topics, when possible.

Objectives

  • Describe the epidemiological evidence supporting the case for the involvement of obesity or related comorbidities in MS risk and prognosis. 

  • Describe the biological mechanisms, including metabolism, related to obesity and its comorbidities that may be detrimental to outcomes among people with MS. 

  • Describe the results of clinical trials that have focused on improving metabolism through diet, as well as some of the challenges of conducting such studies.