Dementia and Aging

Date/Time: Sunday, October 21, 2018 - 3:30 PM to 5:30 PM
Type: Special Interest Group
Area: Dementia and Aging
Room: Regency V

Session Overview

Chair: Jennifer Whitwell, PhD – Mayo Clinic Co-Chair: Eric McDade, DO – University of Pittsburgh Age related neurodegenerative dementias comprise a wide range of syndromes. However, between different syndromes there are shared pathologies and likely shared mechanisms leading to the development of distinct diseases, yet, within diseases a significant variability in phenotypic expression. The 2018 Dementia and Aging SIG will highlight work exploring common mechanisms leading to the development of proteopathies with aging, the non-random distribution and progression of pathology, and the complex genetic risks that contribute to the development of dementia and the differences in clinical symptoms within specific dementias.

Objectives

  • Understand the role autophagy plays in neurodegenerative disease.

  • Discuss current hypothesized mechanisms that proteins spread through the brain.

  • Understand the complex genetic risks that contribute to the development of Alzheimer's disease.